Drug Discovery Director

hace 1 semana

Pamplona, Navarra, España LIM GLOBAL A tiempo completo
Pamplona

Cima is a translational research institute of the University of Navarra, based in Pamplona, Spain.
address unmet medical needs.

Main Responsibilities:

  • Participate in the Steering Committee, responsible for the internal scouting process to identify projects with small molecules, with potential for early development and
optimization.

  • Coordinate the full drug discovery process, once a new target or mechanism of action has been discovered, until a new family of molecules has been patented.
  • Confirmation of the validity, in vitro and in vivo, in terms of efficacy and safety of the new molecules and targets or mechanisms of action of clinical interest.
  • The selected professional will be directly responsible for the design of the families of target molecules.
  • Will participate in the coordination of all the teams and tasks involved in the drug discovery process, such as:
a. Obtaining and expressing target proteins.
b. Biochemical and biophysical assays between targets and ligands.
c. Design of the families of molecules.
d. Computational studies, including studies with artificial intelligence.
e. Supervision of the CRO in charge of the synthesis of molecules.
f. Management of all regulatory preclinical, PK-PD, ADMET studies.
g. IP coordination.

  • Lead the drug design process.

Required Qualifications & Experience:

  • Participate in the BD and IP committees.
  • Ph.
D. in chemistry or pharmacy with postdoctoral training in medicinal chemistry.

  • 10+ years of drug discovery experience.
  • 6+ years of drug design experience and should have detailed knowledge of the drug discovery process.
  • Additional experience in computational and AI studies will be an asset.
  • Track record of patented molecules.
  • Ability to work crossfunctionally with a variety of departments, functions and stakeholders.
  • Strong persuasion and negotiation skills.
  • Effective communication of project status, science, and strategy to a variety of internal and external audiences.
  • Fluency in English is a must, Spanish is preferred.

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